(Sep 2) The Texas State Bobcats beat the Baylor Bears as a 26.5 point road underdog.
(Nov 18) The New Mexico State Aggies beat the Auburn Tigers as a 25.5 point road underdog.
(Oct 21) The Virginia Cavaliers beat the North Carolina Tar Heels as a 24 point road underdog.
(Sep 9) The Fordham Rams beat the Buffalo Bulls as a 23.5 point road underdog.
(Nov 11) The Hawai'i Rainbow Warriors beat the Air Force Falcons as a 22.5 point home underdog.
(Nov 18) The New Mexico Lobos beat the Fresno State Bulldogs as a 22.5 point road underdog.
(Sep 30) The Bowling Green Falcons beat the Georgia Tech Yellow Jackets as a 21 point road underdog.
(Sep 2) The Colorado Buffaloes beat the TCU Horned Frogs as a 20.5 point road underdog.
(Oct 7) The Georgia Tech Yellow Jackets beat the Miami Hurricanes as a 19 point road underdog.
(Sep 23) The Central Michigan Chippewas beat the South Alabama Jaguars as a 16.5 point road underdog.
(Sep 16) The Miami (OH) RedHawks beat the Cincinnati Bearcats as a 14.5 point road underdog.
(Nov 11) The Arizona State Sun Devils beat the UCLA Bruins as a 14 point road underdog.
(Sep 30) The West Virginia Mountaineers beat the TCU Horned Frogs as a 14 point road underdog.
(Oct 28) The Northwestern Wildcats beat the Maryland Terrapins as a 14.0 point home underdog.
(Oct 14) The Illinois Fighting Illini beat the Maryland Terrapins as a 13.5 point road underdog.
(Oct 13) The Stanford Cardinal beat the Colorado Buffaloes as a 13 point road underdog.
(Sep 2) The Wyoming Cowboys beat the Texas Tech Red Raiders as a 13.0 point home underdog.
(Nov 4) The Stanford Cardinal beat the Washington State Cougars as a 13 point road underdog.
(Sep 4) The Duke Blue Devils beat the Clemson Tigers as a 12.5 point home underdog.
(Oct 28) The Georgia Tech Yellow Jackets beat the North Carolina Tar Heels as a 12.0 point home underdog.
(Oct 6) The Oklahoma State Cowboys beat the Kansas State Wildcats as a 11.5 point home underdog.
(Sep 23) The Northwestern Wildcats beat the Minnesota Golden Gophers as a 11.5 point home underdog.
(Oct 28) The Louisiana Ragin' Cajuns beat the South Alabama Jaguars as a 11.5 point road underdog.
(Oct 21) The Nevada Wolf Pack beat the San Diego State Aztecs as a 11 point road underdog.
(Sep 9) The Florida International Golden Panthers beat the North Texas Mean Green as a 10.5 point home underdog.
(Dec 29) The Memphis Tigers beat the Iowa State Cyclones as a 10.5 point road underdog.
(Nov 18) The Appalachian State Mountaineers beat the James Madison Dukes as a 10 point road underdog.
(Oct 7) The Connecticut Huskies beat the Rice Owls as a 10 point road underdog.
(Oct 28) The UMass Minutemen beat the Army Black Knights as a 10 point road underdog.
Out of 415 games with spreads of 10 or higher, 29 teams, or 6.99% were able to pull off the outright victory.