Save the Vig - Biggest Upsets as of Week 1
A look at 2019's Biggest Upsets.

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(Oct 19)    The Illinois Fighting Illini beat the Wisconsin Badgers as a 28.5 point home underdog.
(Oct 12)    The Bowling Green Falcons beat the Toledo Rockets as a 26.5 point home underdog.
(Sep 14)    The The Citadel Bulldogs beat the Georgia Tech Yellow Jackets as a 25.5 point road underdog.
(Aug 31)    The Georgia State Panthers beat the Tennessee Volunteers as a 24.5 point road underdog.
(Oct 26)    The Kansas State Wildcats beat the Oklahoma Sooners as a 23.5 point home underdog.
(Oct 19)    The Vanderbilt Commodores beat the Missouri Tigers as a 21.0 point home underdog.
(Nov 23)    The Florida International Golden Panthers beat the Miami Hurricanes as a 21.0 point home underdog.
(Oct 12)    The South Carolina Gamecocks beat the Georgia Bulldogs as a 20.5 point road underdog.
(Sep 21)    The San José State Spartans beat the Arkansas Razorbacks as a 20 point road underdog.
(Sep 13)    The Kansas Jayhawks beat the Boston College Eagles as a 18.5 point road underdog.
(Oct 19)    The Georgia Tech Yellow Jackets beat the Miami Hurricanes as a 18 point road underdog.
(Nov 9)    The Nevada Wolf Pack beat the San Diego State Aztecs as a 17 point road underdog.
(Sep 21)    The UCLA Bruins beat the Washington State Cougars as a 17 point road underdog.
(Nov 8)    The Tulsa Golden Hurricane beat the UCF Knights as a 17.0 point home underdog.
(Oct 12)    The UNLV Rebels beat the Vanderbilt Commodores as a 16.5 point road underdog.
(Aug 31)    The Wyoming Cowboys beat the Missouri Tigers as a 16.5 point home underdog.
(Nov 9)    The Illinois Fighting Illini beat the Michigan State Spartans as a 15.5 point road underdog.
(Sep 14)    The Arizona State Sun Devils beat the Michigan State Spartans as a 15.5 point road underdog.
(Oct 31)    The Georgia Southern Eagles beat the Appalachian State Mountaineers as a 15 point road underdog.
(Nov 16)    The West Virginia Mountaineers beat the Kansas State Wildcats as a 14 point road underdog.
(Nov 29)    The West Virginia Mountaineers beat the TCU Horned Frogs as a 14 point road underdog.
(Nov 23)    The Colorado Buffaloes beat the Washington Huskies as a 14.0 point home underdog.
(Oct 5)    The Virginia Tech Hokies beat the Miami Hurricanes as a 14 point road underdog.
(Sep 21)    The Buffalo Bulls beat the Temple Owls as a 14.0 point home underdog.
(Sep 7)    The California Golden Bears beat the Washington Huskies as a 13.5 point road underdog.
(Oct 26)    The Colorado State Rams beat the Fresno State Bulldogs as a 13.5 point road underdog.
(Oct 5)    The Stanford Cardinal beat the Washington Huskies as a 13.5 point home underdog.
(Nov 23)    The Nevada Wolf Pack beat the Fresno State Bulldogs as a 13.5 point road underdog.
(Nov 23)    The Arizona State Sun Devils beat the Oregon Ducks as a 13.0 point home underdog.
(Nov 16)    The Rice Owls beat the Middle Tennessee Blue Raiders as a 13 point road underdog.
(Oct 26)    The Oklahoma State Cowboys beat the Iowa State Cyclones as a 11.5 point road underdog.
(Aug 30)    The Nevada Wolf Pack beat the Purdue Boilermakers as a 11.0 point home underdog.
(Nov 29)    The South Alabama Jaguars beat the Arkansas State Red Wolves as a 10.5 point home underdog.
(Oct 26)    The Kentucky Wildcats beat the Missouri Tigers as a 10.0 point home underdog.
(Aug 24)    The Hawai'i Rainbow Warriors beat the Arizona Wildcats as a 10.0 point home underdog.
(Oct 19)    The Oregon State Beavers beat the California Golden Bears as a 10 point road underdog.
(Nov 26)    The Northern Illinois Huskies beat the Western Michigan Broncos as a 10.0 point home underdog.
(Aug 29)    The Central Arkansas Bears beat the Western Kentucky Hilltoppers as a 10 point road underdog.
(Oct 26)    The San José State Spartans beat the Army Black Knights as a 10 point road underdog.

There have been 39 upsets by teams that were 10 point underdogs or more in the 2019 regular season.
Out of 452 games with spreads of 10 or higher, 39 teams, or 8.63% were able to pull off the outright victory.